CLIC2 Antikörper (AA 51-150) (Cy3)

Produktnummer ABIN1702281

Dieses Anti-CLIC2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CLIC2 in IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für CLIC2 Antikörper (AA 51-150) (Cy3) (ABIN1702281)

Target: CLIC2 (Chloride Intracellular Channel 2 (CLIC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLIC2 Antikörper ist konjugiert mit Cy3

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CLIC2 Antikörper (Cy3)

Bindungsspezifität: AA 51-150

Homologie: Human,Rat,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLIC2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CLIC2

Target: CLIC2 (Chloride Intracellular Channel 2 (CLIC2))

Andere Bezeichnung: CLIC2

Hintergrund:

Synonyms: Chloride intracellular channel 2, Chloride intracellular channel protein 2, CLIC 2b, CLIC2, CLIC2_HUMAN, CLIC2b, MRXS32, OTTHUMP00000196471, XAP 121, XAP121.

Background: Chloride channels (CLCs) regulate cellular traffic of chloride ions, a critical component of all living cells. CLCs are involved in membrane potential stabilization, signal transduction, cell volume regulation and organic solute transport. The putative 247 amino acid protein chloride intracellular channel 2 (CLIC2), also designated XAP121, shares 60 % identity with the CLIC1 protein and demonstrates expression in only fetal liver and adult skeletal muscle tissues. The CLIC2 gene maps to chromosome Xq28 and contains 6 exons. Because a direct association exists between a number of human chloride channel genes and a range of hereditary diseases, CLIC2 is a potential candidate for one of the many diseases linked to Xq28. The hereditary form of incontinentia pigmenti (IP2), for example, is a rare disorder characterized by abnormalities of the tissues and organs derived from the ectoderm and neuroectoderm that has been linked to Xq28

Pathways: Negative Regulation of Transporter Activity