DVL2 Antikörper (pSer143) (Cy3)

Produktnummer ABIN1702267

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DVL2 in WB, IF (p) und IF (cc). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für DVL2 Antikörper (pSer143) (Cy3) (ABIN1702267)

Target: DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DVL2 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-DVL2 Antikörper (Cy3)

Bindungsspezifität: pSer143

Verwendungszweck: phospho-Dishevelled 2 (Ser143) Polyclonal Antibody, Cy3 Conjugated

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Dishevelled 2 around the phosphorylation site of Ser143

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DVL2

Target: DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

Andere Bezeichnung: Dishevelled 2

Hintergrund:

Synonyms: Segment polarity protein dishevelled homolog DVL-2, Dishevelled-2, DSH homolog 2, DVL2

Background: Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity).

Gen-ID: 1856

Pathways: Tube Formation