POLM Antikörper (AA 261-360) (Cy3)
Kurzübersicht für POLM Antikörper (AA 261-360) (Cy3) (ABIN1702076)
Target
Alle POLM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 261-360
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Kreuzreaktivität
- Human
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Homologie
- Mouse,Rat,Horse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human DNA polymerase mu
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- POLM (Polymerase (DNA Directed), mu (POLM))
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Andere Bezeichnung
- DNA polymerase mu
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Hintergrund
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Synonyms: DNA Polymerase Mu, DNA-directed DNA polymerase mu, DNA-directed DNA/RNA polymerase mu, DPOLM_HUMAN, FLJ35482, Pol iota, Pol Mu, Polm, POLM protein, Polymerase DNA directed mu, Polymerase DNA directed mu, Tdt N, Tdt-N, TdtN, Terminal transferase.
Background: DNA polymerase mu shares a number of characteristics with DNA polymerase Beta as well as with terminal deoxynucleotideyltransferase. Pol mu purportedly plays a role in microhomology mediated joining and the repair of double-stranded breaks. However, unlike other DNA polymerases, which show substrate specificity for deoxynucleotides, DNA Pol mu incorporates both deoxynucleotides and ribonucleotides in a template- directed manner. This unusual capability implies a novel role for this polymerase in DNA repair.
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Gen-ID
- 27434
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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