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POLM Antikörper (AA 261-360) (Cy3)

This anti-POLM antibody (ABIN1702076) is a Rabbit Polyclonal antibody detecting POLM in WB, IF (cc), IF (p). Suitable for Human.
Produktnummer ABIN1702076

Kurzübersicht für POLM Antikörper (AA 261-360) (Cy3) (ABIN1702076)

Target

Alle POLM Antikörper anzeigen
POLM (Polymerase (DNA Directed), mu (POLM))

Reaktivität

  • 20
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 20
Kaninchen

Klonalität

  • 20
Polyklonal

Konjugat

  • 7
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser POLM Antikörper ist konjugiert mit Cy3

Applikation

  • 19
  • 12
  • 12
  • 5
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 261-360

    Kreuzreaktivität

    Human

    Homologie

    Mouse,Rat,Horse

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human DNA polymerase mu

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    POLM (Polymerase (DNA Directed), mu (POLM))

    Andere Bezeichnung

    DNA polymerase mu

    Hintergrund

    Synonyms: DNA Polymerase Mu, DNA-directed DNA polymerase mu, DNA-directed DNA/RNA polymerase mu, DPOLM_HUMAN, FLJ35482, Pol iota, Pol Mu, Polm, POLM protein, Polymerase DNA directed mu, Polymerase DNA directed mu, Tdt N, Tdt-N, TdtN, Terminal transferase.

    Background: DNA polymerase mu shares a number of characteristics with DNA polymerase Beta as well as with terminal deoxynucleotideyltransferase. Pol mu purportedly plays a role in microhomology mediated joining and the repair of double-stranded breaks. However, unlike other DNA polymerases, which show substrate specificity for deoxynucleotides, DNA Pol mu incorporates both deoxynucleotides and ribonucleotides in a template- directed manner. This unusual capability implies a novel role for this polymerase in DNA repair.

    Gen-ID

    27434

    Pathways

    DNA Reparatur, Production of Molecular Mediator of Immune Response
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