GNPDA1 Antikörper (AA 201-289) (Biotin)

Produktnummer ABIN1701526

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GNPDA1 in WB, ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für GNPDA1 Antikörper (AA 201-289) (Biotin) (ABIN1701526)

Target: GNPDA1 (Glucosamine-6-Phosphate Deaminase 1 (GNPDA1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNPDA1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GNPDA1 Antikörper (Biotin)

Bindungsspezifität: AA 201-289

Kreuzreaktivität: Maus

Homologie: Human,Rat,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNPDA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu GNPDA1

Target: GNPDA1 (Glucosamine-6-Phosphate Deaminase 1 (GNPDA1))

Andere Bezeichnung: GNPDA1

Hintergrund:

Synonyms: EC 3.5.99.6, GlcN6P deaminase 1, Glucosamine 6 phosphate deaminase 1, Glucosamine 6 phosphate isomerase 1, Glucosamine-6-phosphate deaminase 1, Glucosamine-6-phosphate isomerase 1, GNPDA 1, GNPDA1, GNPI, GNPI1_HUMAN, HLN, KIAA0060, Oscillin, Putative glucosamine 6 phosphate isomerase.

Background: During fertilization in mammals, the sperm activates the egg by causing an increase in the level of free cytoplasmic calcium concentration. This increased calcium concentration induces a characteristic series of oscillations that trigger egg activation and early embryo development. A hamster protein named oscillin is thought to be involved in this pathway. The enzyme glucosamine-6-phosphate isomerase (GNPI) or deaminase (GNPDA1) and the related protein GNPDA2 are the human homologs of hamster oscillin. GNPDA1 and GNPDA2 catalyze the conversion of GNP to fructose-6-phosphate and ammonia. Both proteins exist as homohexamers and are ubiquitously expressed with highest expression in testis, ovary and heart. Three isoforms of GNPDA2 are expressed due to alternative splicing events.

Gen-ID: 10007