GALE Antikörper (AA 21-120) (Biotin)

Produktnummer ABIN1701447

Dieses Anti-GALE-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GALE in WB, ELISA, IHC (p) und IHC (fro). Geeignet für Maus.

Kurzübersicht für GALE Antikörper (AA 21-120) (Biotin) (ABIN1701447)

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GALE Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GALE Antikörper (Biotin)

Bindungsspezifität: AA 21-120

Kreuzreaktivität: Maus

Homologie: Human,Rat,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GALE/Galactowaldenase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu GALE

Target: GALE (UDP-Galactose-4-Epimerase (GALE))

Andere Bezeichnung: GALE/Galactowaldenase

Hintergrund:

Synonyms: FLJ95174, FLJ97302, Galactose 4 epimerase UDP, Galactowaldenase, galE, GALE_HUMAN, OTTHUMP00000002991, OTTHUMP00000002994, OTTHUMP00000037931, OTTHUMP00000044857, SDR1E1, short chain dehydrogenase/reductase family 1E member 1, UDP galactose 4 epimerase, UDP glucose 4 epimerase, UDP-galactose 4-epimerase, UDP-glucose 4-epimerase.

Background: GALE is a 348 amino acid protein that functions as the third enzyme in the Leloir pathway of galactose metabolism. A member of the sugar epimerase family, GALE exists as a homodimer, binds FAD as a cofactor and catalyzes the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine and UDP-glucose to UDP-galactose. The gene encoding GALE maps to human chromosome 1p36.11 and mutations in this gene lead to the development of complex disorder known as epimerase-deficiency galactosemia (EDG) or galactosemia type 3, which is characterized by mental retardation, liver damage, cataracts and deafness.

Gen-ID: 2582

Pathways: Response to Water Deprivation, Cellular Glucan Metabolic Process