GNL3L Antikörper (AA 210-310) (Biotin)
Kurzübersicht für GNL3L Antikörper (AA 210-310) (Biotin) (ABIN1701314)
Target
Alle GNL3L Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 210-310
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Kreuzreaktivität
- Maus, Ratte
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Homologie
- Human,Dog,Cow,Pig,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human GNL3L
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Isotyp
- IgG
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Applikationshinweise
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IHC-P 1:200-400
IHC-F 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
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Andere Bezeichnung
- GNL3L
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Hintergrund
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Synonyms: GNL3L_HUMAN, FLJ10613, Guanine nucleotide binding protein-like 3 nucleolar-like, novel GTPase, OTTHUMP00000023374.
Background: GTPases from the MMR1/HSR1 GTP-binding protein subfamily are circularly rearranged G-motifs that play a critical role in maintaining normal cell growth. Deletion of these genes results in severe growth defects with a marked reduction in mature rRNA species and a concomitant accumulation of the 35S pre-rRNA transcript. Deletion also causes the ribosomal protein Rpl25a to fail exportation from the nucleolus. Deletion of any of the G-domain motifs will result in a null phenotype and nuclear/nucleolar localization that lacks the nucleolar export of preribosomes and is accompanied by a distortion of the nucleolar structure. GNL3L (guanine nucleotide binding protein-like 3 (nucleolar)-like) is a 582 amino acid nuclear protein that belongs to the MMR1/HSR1 GTP-binding protein family. Containing one G (guanine nucleotide-binding) domain, GNL3L is required for normal processing of ribosomal pre-rRNA and for cell proliferation.
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Gen-ID
- 54552
Target
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