FMO3 Antikörper (AA 111-210) (Biotin)

Produktnummer ABIN1700865

Dieses Anti-FMO3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FMO3 in WB, ELISA, IHC (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für FMO3 Antikörper (AA 111-210) (Biotin) (ABIN1700865)

Target: FMO3 (Flavin Containing Monooxygenase 3 (FMO3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FMO3 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-FMO3 Antikörper (Biotin)

Bindungsspezifität: AA 111-210

Homologie: Human,Mouse,Rat,Cow,Monkey

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FMO3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu FMO3

Target: FMO3 (Flavin Containing Monooxygenase 3 (FMO3))

Andere Bezeichnung: FMO3

Hintergrund:

Synonyms: Dimethylaniline monooxygenase [N oxide forming] 3, Dimethylaniline monooxygenase [N-oxide-forming] 3, Dimethylaniline monooxygenase 3, Dimethylaniline oxidase 3, dJ127D3.1, Flavin containing monooxygenase 3, FMO 3, FMO form 2, FMO II, FMO3, FMO3_HUMAN, FMOII, Hepatic flavin containing monooxygenase 3, Hepatic flavin-containing monooxygenase 3, MGC34400, TMAU, Trimethylamine monooxygenase.

Background: The Flavin containing monooxygenase family consists of five gene products, FMO1-5, that are major enzymatic oxidants involved in the metabolism of various therapeutics. Located in the liver, FMO3 is a hepatic microsomal enzyme that oxygenates soft nucleophiles such as secondary and tertiary amines. Through its N-oxygenase capabilities, FMO3 acts on a variety of xenobiotics to catalyze oxidative digestion. Defects in the FMO3 gene are the primary cause of trimethylaminuria (TMAuria), an inborn error of metabolism associated with a fishy body odor emitting from sweat, urine and breath. Genetic mutations in FMO3 lead to the N-oxidation of amino-trimethylamine derived from food products, thus producing the malodor associated with TMAuria.

Gen-ID: 2328