C1orf55 Antikörper (AA 51-150) (Biotin)

Produktnummer ABIN1700621

Der Kaninchen Polyklonal Anti-C1orf55-Antikörper wurde für WB, IHC (p), ELISA und IHC (fro) validiert. Er ist geeignet, C1orf55 in Proben von Human zu detektieren.

Kurzübersicht für C1orf55 Antikörper (AA 51-150) (Biotin) (ABIN1700621)

Target: C1orf55 (Chromosome 1 Open Reading Frame 55 (C1orf55))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1orf55 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-C1orf55 Antikörper (Biotin)

Bindungsspezifität: AA 51-150

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf55

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu C1orf55

Target: C1orf55 (Chromosome 1 Open Reading Frame 55 (C1orf55))

Andere Bezeichnung: C1orf55

Hintergrund:

Synonyms: C1orf55, CA055_HUMAN, Chromosome 1 open reading frame 55, dJ671D7.1, FLJ35382, Hypothetical protein LOC163859, RP4 671D7.1, UPF0667 protein C1orf55.

Background: Belonging to the UPF0667 family, C1orf55 is a 451 amino acid protein that is phosphorylated upon DNA damage, likely by Atm or ATR. There are three different isoforms of C1orf55 that are produced as a result of alternative splicing events. The gene encoding C1orf55 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

Gen-ID: 163859