AES Antikörper (AA 21-120) (Biotin)

Produktnummer ABIN1700510

Der Kaninchen Polyklonal Anti-AES-Antikörper wurde für ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, AES in Proben von Human zu detektieren.

Kurzübersicht für AES Antikörper (AA 21-120) (Biotin) (ABIN1700510)

Target: AES (Amino-terminal Enhancer of Split (AES))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AES Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-AES Antikörper (Biotin)

Bindungsspezifität: AA 21-120

Homologie: Human,Mouse,Rat,Cow,Sheep,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TLE5/Amino-terminal enhancer of split

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu AES

Target: AES (Amino-terminal Enhancer of Split (AES))

Andere Bezeichnung: TLE5/Amino-terminal enhancer of split

Hintergrund:

Synonyms: Aes 1, Amino-terminal enhancer of split , Aes 2, aes, AES_HUMAN, Aes1, Aes2, Amino Enhancer of Split, Amino terminal enhancer of split, Amino-terminal enhancer of split, Esp 1, Esp1, Gp130 associated protein GAM, Gp130-associated protein GAM, GRG 5, GRG, GRG protein, GRG5, Protein ESP 1, Protein ESP1, Protein GRG, TLE 5, TLE5.

Background: TLE5 is a 197 amino acid nuclear protein that belongs to the TLE family. Expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle, TLE5 functions as either a homooligomer or a heterooligomer with other TLE family members and, through this association, dominantly represses the expression of TLE genes. In addition, TLE5 can repress NFkB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events. Two isoforms of TLE5 exist due to alternative splicing events.

Gen-ID: 166

Pathways: WNT Signalweg, SARS-CoV-2 Protein Interaktom