AHNAK Antikörper (AA 1351-1450) (Biotin)

Produktnummer ABIN1700195

Der Kaninchen Polyklonal Anti-AHNAK-Antikörper wurde für ELISA, IHC (fro) und IHC (p) validiert. Er ist geeignet, AHNAK in Proben von Human zu detektieren.

Kurzübersicht für AHNAK Antikörper (AA 1351-1450) (Biotin) (ABIN1700195)

Target: AHNAK (AHNAK Nucleoprotein (AHNAK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AHNAK Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-AHNAK Antikörper (Biotin)

Bindungsspezifität: AA 1351-1450

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AHNAK

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu AHNAK

Target: AHNAK (AHNAK Nucleoprotein (AHNAK))

Andere Bezeichnung: AHNAK

Hintergrund:

Synonyms: AHNAK, AHNAK nucleoprotein desmoyokin, AHNAKRS, AHNK_HUMAN, Desmoyokin, Fragments, MGC5395, Neuroblast dferentiation associated protein AHNAK, Neuroblast dferentiation-associated protein AHNAK, PM227.

Background: AHNAK is a 5,890 amino acid protein encoded by the human gene AHNAK. The intronless AHNAK gene is located on human chromosome 11q12 and has three main structural regions: the 251 amino acid N-terminus, a large central region of 4390 amino acids with multiple repeated units of about 128 amino acids in length, and the 1002 amino acid C-terminus. The central region seems to have antiparallel beta-strands connected by intervening loops. Several putative regulatory elements are clustered within the C-terminal region, including nuclear export localization signals, a leucine zipper, and potential phosphorylation sites for Akt1 and PKC. AHNAK is believed to be an important signalling molecule involved in a wide range of physiological activities and may be required for neuronal cell differentiation.. AHNAK also appears to influence b-adrenergic regulation of cardiac L-type Ca2+ channel function.