CSGALNACT1 Antikörper (AA 101-200) (AbBy Fluor® 647)

Produktnummer ABIN1698820

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CSGALNACT1 in IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CSGALNACT1 Antikörper (AA 101-200) (AbBy Fluor® 647) (ABIN1698820)

Target: CSGALNACT1 (Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1 (CSGALNACT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSGALNACT1 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CSGALNACT1 Antikörper (AbBy Fluor® 647)

Bindungsspezifität: AA 101-200

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CSGALNACT1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CSGALNACT1

Target: CSGALNACT1 (Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1 (CSGALNACT1))

Andere Bezeichnung: CSGALNACT1

Hintergrund:

Synonyms: 4-N-acetylgalactosaminyltransferase 1, Beta4GalNAcT 1, beta4GalNAcT, Beta4GalNAcT-1, Beta4GalNAcT1, CGAT1_HUMAN, ChGn, Chondroitin beta-1, Chondroitin beta1 4 N acetylgalactosaminyltransferase, Chondroitin beta1 4 N acetylgalactosaminyltransferase 1, Chondroitin sulfate N acetylgalactosaminyltransferase 1, Chondroitin sulfate N-acetylgalactosaminyltransferase 1, CSGalNAcT 1, CsGalNAcT-1, Csgalnact1, FLJ11264, FLJ13760.

Background: The chondroitin N-acetylgalactosaminyltransferase family includes Beta-1,4-GalNAc-T, Beta-1,4-GalNAc-T2, Beta-1,4-GalNAc-T3 and Beta-1,4-GalNAc-T4. The Beta-1,4-GalNAc-T protein consists of a short N-terminal residue, a transmembrane region and a long C-terminal residue, which includes a catalytic domain and localizes to the Golgi apparatus. Beta-1,4-GalNAc-T utilizes simple ganglioside GM3 as a substrate for more complex gangliosides GM2, GM1 and GD1a. Beta-1,4-GalNAc-T is expressed in normal brain tissues and in various malignant transformed cells, such as malignant melanoma, neuroblastoma and adult T cell leukemia. Mice lacking the Beta-1,4-GalNAc-T protein develop significant and progressive behavioral neuropathies, including deficits in reflexes, strength, coordination and balance. Beta-1,4-GalNAc-T is a potential molecular marker for detecting melanoma cells and monitoring tumor progression.

Gen-ID: 55790

Pathways: Glycosaminoglycan Metabolic Process