CPA3 Antikörper (AA 101-200) (AbBy Fluor® 555)

Produktnummer ABIN1696626

Dieses Anti-CPA3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CPA3 in WB, IF (cc) und IF (p). Geeignet für Ratte.

Kurzübersicht für CPA3 Antikörper (AA 101-200) (AbBy Fluor® 555) (ABIN1696626)

Target: CPA3 (Carboxypeptidase A3 (Mast Cell) (CPA3))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPA3 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CPA3 Antikörper (AbBy Fluor® 555)

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Ratte

Homologie: Human,Mouse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CPA3/MC-CPA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CPA3

Target: CPA3 (Carboxypeptidase A3 (Mast Cell) (CPA3))

Andere Bezeichnung: CPA3/MC-CPA

Hintergrund:

Synonyms: carboxypeptidase A, Carboxypeptidase A3, carboxypeptidase A3 mast cell, CBPA3_HUMAN, Cpa3, Mast cell carboxypeptidase A, mast cell carboxypeptidase A3, MC CPA, MC-CPA.

Background: Carboxypeptidase A (CPA) is a pancreatic exopeptidase which hydrolyses the peptide bond adjacent to the C-terminal end in polypeptide chains. Mast cell carboxypeptidase A (MC-CPA), a part of the peptidase M14 family, is a highly conserved metalloprotease localized to the secretory granules, along with trytases and chymases. MC-CPA is stored as an active enzyme in the granule and is released, along with other inflammatory mediators, upon mast cell degranulation. MC-CPA mirrors pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues. The optimum pH of MC-CPA is between neutral and basic, depending upon the substrate. The MC-CPA gene, CPA3, resides on chromosome 3 and contains 11 exons.

Gen-ID: 1359

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones