PA2G4 Antikörper (AA 201-320) (AbBy Fluor® 350)

Produktnummer ABIN1693534

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PA2G4 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für PA2G4 Antikörper (AA 201-320) (AbBy Fluor® 350) (ABIN1693534)

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PA2G4 Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PA2G4 Antikörper (AbBy Fluor® 350)

Bindungsspezifität: AA 201-320

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Sheep,Pig,Chicken,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EBP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PA2G4

Target: PA2G4 (Proliferation-Associated 2G4, 38kDa (PA2G4))

Andere Bezeichnung: EBP1

Hintergrund:

Synonyms: AA672939, Cell cycle protein p38 2G4 homolog, Cell cycle protein p38-2G4 homolog, ErbB-3 binding protein 1, ErbB3 binding protein 1, ErbB3-binding protein 1, ErbB3-binding protein Ebp1, hG4 1, hG4-1, IRES-specic cellular trans-acting factor 45 kDa, MGC81621, MGC94070, Mpp1, p38 2G4, PA2G4, PA2G4_HUMAN, Plfap, proliferation associated 2G4, proliferation associated 2G4, 38-KD, proliferation-associated 2G4, 38 kDa, proliferation-associated 2G4, a, proliferation-associated protein 1, proliferation-associated protein 2G4, Protein p38-2G4, si:dz150i12.2, wu:fb19b11, wu:ft56d05, zgc:86732.

Background: EBP1 is a member of the peptidase M24C family and functions as an RNA-binding protein involved in cellular proliferation and differentiation processes. It is expressed in a variety of cell lines, including a wide range of tumor cell lines, and localizes to the cytoplasm. Upon treatment with Neuregulin-1 (heregulin), EBP1 translocates to the nucleus. EBP1 is a component of pre-ribosomal ribonucleoprotein complexes, participating in ribosome assembly and regulating the later steps of rRNA processing. In addition, EBP1 interacts with ErbB-3 and may function as a modulator of the ErbB-3-mediated signal transduction pathway by regulating the effects of Neuregulin-1 (heregulin). EBP1 also associates with histone deacetylases (HDACs), functioning as a transcriptional co-repressor of cell cycle regulatory genes.

Gen-ID: 5036

Pathways: Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades