PDE8A Antikörper
Kurzübersicht für PDE8A Antikörper (ABIN1690735)
Target
Alle PDE8A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- Anti-PDE8A Purified
-
Spezifität
- The mouse monoclonal antibody EM-52 recognizes PDE8a (phosphodiesterase 8 A), an approximately 93 kDa intracellular enzyme that hydrolyzes cAMP to 5'AMP.
-
Kreuzreaktivität (Details)
- Human
-
Aufreinigung
- Purified by protein-A affinity chromatography.
-
Reinheit
- > 95 % (by SDS-PAGE)
-
Immunogen
- Human PDE8a
-
Isotyp
- IgG1 kappa
-
-
-
-
Applikationshinweise
- Western blotting: Recommended dilution: 1-2 μg/mL.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1 mg/mL
-
Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Do not freeze.
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
-
-
- PDE8A (phosphodiesterase 8A (PDE8A))
-
Andere Bezeichnung
- PDE8A
-
Hintergrund
- Phosphodiesterase 8A,PDE8a (high affinity cAMP-specific and IBMX-insensitive 3´,5´-cyclic phosphodiesterase 8 A) is a cyclic nucleotide phosphodiesterase, which hydrolyzes cAMP, an important regulator and mediator of multiple cellular responses to extracellular signals. It is expressed in a wide variety of tissues including testis, ovary, small intestine, and colon. It is not expressed e.g. in thymus. PDE8a is composed of C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.,HsT19550
-
Gen-ID
- 5151
-
UniProt
- O60658
-
Pathways
- cAMP Metabolic Process
Target
-