Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PR Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human und wurde in 5+ Publikationen erwähnt.
Produktnummer ABIN1689598

Kurzübersicht für PR Antikörper (ABIN1689598)

Target

PR

Reaktivität

  • 8
  • 3
  • 2
  • 1
  • 1
Human

Wirt

  • 6
  • 2
Maus

Klonalität

  • 6
  • 2
Monoklonal

Konjugat

  • 8
Unkonjugiert

Applikation

  • 7
  • 6
  • 5
  • 5
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon

2F12B4-2F12H2
  • Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of PR expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C
  • Jowett: "Safe Motherhood interventions in low-income countries: an economic justification and evidence of cost effectiveness." in: Health policy (Amsterdam, Netherlands), Vol. 53, Issue 3, pp. 201-28, (2000) (PubMed).

    Hagen, Silva, Amorim, Hagedoorn, Wassink, Haaker, Robb: "Novel structure and redox chemistry of the prosthetic groups of the iron-sulfur flavoprotein sulfide dehydrogenase from Pyrococcus furiosus; evidence for a [2Fe-2S] cluster with Asp(Cys)3 ligands." in: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 5, Issue 4, pp. 527-34, (2000) (PubMed).

    Wen, Xu, Mais, Goldman, McDonnell: "The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells." in: Molecular and cellular biology, Vol. 14, Issue 12, pp. 8356-64, (1994) (PubMed).

    McGuire: "Prognostic factors in primary breast cancer." in: Cancer surveys, Vol. 5, Issue 3, pp. 527-36, (1987) (PubMed).

    Bach: "Markets in kidneys." in: Lancet, Vol. 2, Issue 8411, pp. 1102, (1984) (PubMed).

  • Target

    PR

    Hintergrund

    PR(progesterone receptor), with 933-amino acid protein (about 110kDa), a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone, PR is mediated by two functionally different isoforms of the progesterone receptor, the full length PR-B and the short form PR-A. The PR-A and PR-B proteins are 94 kDa and 114 kDa respectively. That are equimolar in the normal breast but dysregulated in advanced disease. PR is prognostic markers in breast cancers irrespective of the patient's progestational status Human progesterone.
    Synonyms: PR, NR3C3, PGR

    Gen-ID

    5241
Sie sind hier:
Chat with us!