TIMELESS Antikörper (AA 969-1208)

Produktnummer ABIN1683038

Der Kaninchen Polyklonal Anti-TIMELESS-Antikörper wurde für WB und IHC validiert. Er ist geeignet, TIMELESS in Proben von Human zu detektieren.

Kurzübersicht für TIMELESS Antikörper (AA 969-1208) (ABIN1683038)

Target: TIMELESS (Timeless Homolog (TIMELESS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMELESS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TIMELESS Antikörper

Bindungsspezifität: AA 969-1208

Sequenz: EDLEEEENLP EEDSEEEEEG GSEAEQVQGS LVLSNENLGQ SLHQEGFSIP LLWLQNCLIR AADDREEDGC SQAVPLVPLT EENEEAMENE QFQQLLRKLG VRPPASGQET FWRIPAKLSP TQLRRAAASL SQPEEEQKLQ PELQPKVPGE QGSDEEHCKE HRAQALRALL LAHKKKAGLA SPEEEDAVGK EPLKAAPKKR QLLDSDEEQE EDEGRNRAPE LGAPGIQKKK RYQIEDDEDD

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 969-1208 of human TIMELESS (NP_003911.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TIMELESS

Target: TIMELESS (Timeless Homolog (TIMELESS))

Andere Bezeichnung: TIMELESS

Hintergrund: The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders.,TIMELESS,TIM,TIM1,hTIM,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Apoptosis,TIMELESS

Molekulargewicht: 138 kDa

Gen-ID: 8914

UniProt: Q9UNS1

Pathways: Protein targeting to Nucleus, Photoperiodism