SAP18 Antikörper (AA 21-172)
Kurzübersicht für SAP18 Antikörper (AA 21-172) (ABIN1682621)
Target
Alle SAP18 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 21-172
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Sequenz
- AVESRVTQEE IKKEPEKPID REKTCPLLLR VFTTNNGRHH RMDEFSRGNV PSSELQIYTW MDATLKELTS LVKEVYPEAR KKGTHFNFAI VFTDVKRPGY RVKEIGSTMS GRKGTDDSMT LQSQKFQIGD YLDIAITPPN RAPPPSGRMR PY
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 21-172 of human SAP18 (NP_005861.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))
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Andere Bezeichnung
- SAP18
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Hintergrund
- Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.,SAP18,2HOR0202,SAP18P,Epigenetics & Nuclear Signaling,SAP18
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Molekulargewicht
- 17 kDa
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Gen-ID
- 10284
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UniProt
- O00422
Target
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