SAP18 Antikörper (N-Term)

Produktnummer ABIN2780718

Produktdetails anti-SAP18 Antikörper

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SAP18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: EIKKEPEKPI DREKTCPLLL RVFTTNNGRH HRMDEFSRGN VPSSELQIYT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SAP18. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SAP18

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 153 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SAP18

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Andere Bezeichnung: SAP18 (SAP18 Produkte)

Synonyme: zgc:73118 antikoerper, C530046K05Rik antikoerper, D11Ertd539e antikoerper, EMegR4 antikoerper, Sinbp1 antikoerper, 2HOR0202 antikoerper, SAP18P antikoerper, Sin3A-associated protein antikoerper, Sin3-associated polypeptide 18 antikoerper, Sin3A associated protein 18 antikoerper, Sin3A associated protein 18kDa S homeolog antikoerper, sap18 antikoerper, Sap18 antikoerper, sap18.S antikoerper, SAP18 antikoerper

Hintergrund: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP18 is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.
Alias Symbols: SAP18P, 2HOR0202
Protein Interaction Partner: INCA1, RBM39, UBC, RNF2, SUZ12, BMI1, CSNK2A2, MAGOH, EIF4A3, VCP, NFIA, SEPT2, MYO1C, IK, HNRNPU, HNRNPC, GTF3C1, SEPT7, CDC5L, U2AF1, SNRPD2, SMARCC2, SMARCB1, SRSF7, SRSF5, SRSF3, SRSF1, SAFB, S100A9, PSAP, NHP2L1, TPR, TFPI, SURF4, SSRP1, SSR3, LOC255
Protein Size: 153

Molekulargewicht: 18 kDa

Gen-ID: 10284

NCBI Accession: NM_005870, NP_005861

UniProt: O00422