PKN1 Antikörper (AA 1-300)

Produktnummer ABIN1682293

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PKN1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PKN1 Antikörper (AA 1-300) (ABIN1682293)

Target: PKN1 (Protein Kinase N1 (PKN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PKN1 Antikörper

Bindungsspezifität: AA 1-300

Sequenz: MASDAVQSEP RSWSLLEQLG LAGADLAAPG VQQQLELERE RLRREIRKEL KLKEGAENLR RATTDLGRSL GPVELLLRGS SRRLDLLHQQ LQELHAHVVL PDPAATHDGP QSPGAGGPTC SATNLSRVAG LEKQLAIELK VKQGAENMIQ TYSNGSTKDR KLLLTAQQML QDSKTKIDII RMQLRRALQA GQLENQAAPD DTQGSPDLGA VELRIEELRH HFRVEHAVAE GAKNVLRLLS AAKAPDRKAV SEAQEKLTES NQKLGLLREA LERRLGELPA DHPKGRLLRE ELAAASSAAF

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PKN1 (NP_002732.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PKN1

Target: PKN1 (Protein Kinase N1 (PKN1))

Andere Bezeichnung: PKN1

Hintergrund: The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.,PKN1,DBK,PAK-1,PAK1,PKN,PKN-ALPHA,PRK1,PRKCL1,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,PKN1

Molekulargewicht: 104 kDa

Gen-ID: 5585

UniProt: Q16512