PKN1 Antikörper (AA 442-620)

Produktnummer ABIN5542353

Produktdetails anti-PKN1 Antikörper

Target: PKN1 (Protein Kinase N1 (PKN1))

Bindungsspezifität: AA 442-620

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PKN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human PKN1 (AA: 442-620) expressed in E. coli.

Klon: 4H10B1

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu PKN1

Target: PKN1 (Protein Kinase N1 (PKN1))

Andere Bezeichnung: PKN1 (PKN1 Produkte)

Synonyme: DBK antikoerper, PAK-1 antikoerper, PAK1 antikoerper, PKN antikoerper, PKN-ALPHA antikoerper, PRK1 antikoerper, PRKCL1 antikoerper, F730027O18Rik antikoerper, Pkn antikoerper, Prkcl1 antikoerper, Stk3 antikoerper, PKN1 antikoerper, 3-2 antikoerper, CG2049 antikoerper, CG2055 antikoerper, CT6637 antikoerper, CT6660 antikoerper, DPKN antikoerper, Dmel\\CG2049 antikoerper, Dpkn antikoerper, PRK2 antikoerper, Pk45C antikoerper, Pk?3 antikoerper, dPKN antikoerper, l(2)06736 antikoerper, l(2)45Ca antikoerper, v(2)rG232 antikoerper, protein kinase N1 antikoerper, protein kinase N1b antikoerper, Protein kinase N antikoerper, PKN1 antikoerper, Pkn1 antikoerper, pkn1b antikoerper, pkn1 antikoerper, Pkn antikoerper

Hintergrund:

Description: The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Aliases: DBK, PKN, PAK1, PRK1, PAK-1, PRKCL1, PKN-ALPHA

Molekulargewicht: 104 kDa

Gen-ID: 5585

HGNC: 5585