IRF4 Antikörper (AA 150-350)
Kurzübersicht für IRF4 Antikörper (AA 150-350) (ABIN1680506)
Target
Alle IRF4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 150-350
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Sequenz
- HPYTMTTPYP SLPAQQVHNY MMPPLDRSWR DYVPDQPHPE IPYQCPMTFG PRGHHWQGPA CENGCQVTGT FYACAPPESQ APGVPTEPSI RSAEALAFSD CRLHICLYYR EILVKELTTS SPEGCRISHG HTYDASNLDQ VLFPYPEDNG QRKNIEKLLS HLERGVVLWM APDGLYAKRL CQSRIYWDGP LALCNDRPNK L
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 150-350 of human IRF4 (NP_002451.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- IRF4 (Interferon Regulatory Factor 4 (IRF4))
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Andere Bezeichnung
- IRF4
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Hintergrund
- The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.,IRF4,LSIRF,MUM1,NF-EM5,SHEP8,IRF-4,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,IRF4
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Molekulargewicht
- 51 kDa
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Gen-ID
- 3662
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UniProt
- Q15306
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Pathways
- Chromatin Binding
Target
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