Cyclin E2 Antikörper (C-Term)

Produktnummer ABIN1679046

Dieses Anti-Cyclin E2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cyclin E2 in WB und IHC. Geeignet für Human.

Kurzübersicht für Cyclin E2 Antikörper (C-Term) (ABIN1679046)

Target: Cyclin E2 (CCNE2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin E2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Cyclin E2 Antikörper

Bindungsspezifität: C-Term

Sequenz: ALCHFTSIEV VKKASGLEWD SISECVDWMV PFVNVVKSTS PVKLKTFKKI PMEDRHNIQT HTNYLAMLEE VNYINTFRKG GQLSPVCNGG IMTPPKSTEK PPGKH

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human Cyclin E2 (NP_477097.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Cyclin E2

Target: Cyclin E2 (CCNE2)

Andere Bezeichnung: CCNE2

Hintergrund: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells.,CCNE2,CYCE2,cyclin E2,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cyclins,G1/S Checkpoint,Hedgehog Signaling Pathway,CCNE2

Molekulargewicht: 41 kDa/46 kDa

Gen-ID: 9134

UniProt: O96020

Pathways: Zellzyklus, Mitotic G1-G1/S Phases