PSPH Antikörper (AA 1-225)

Produktnummer ABIN165446

Produktdetails anti-PSPH Antikörper

Target: PSPH (Phosphoserine Phosphatase (PSPH))

Bindungsspezifität: AA 1-225

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PSPH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Aufreinigung: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Immunogen: Recombinant human PSP (1-225aa) purified from E. coli

Klon: 3G12

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Recommended dilution 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu PSPH

Target: PSPH (Phosphoserine Phosphatase (PSPH))

Andere Bezeichnung: Phosphoserine phosphatase/PSPH (PSPH Produkte)

Hintergrund: Human phosphoserine phosphatase (HPSP), specific for D- and L- phosphoserine, has been identified in all human tissues. HPSP is a Mg (2+) -dependent phosphoserine phosphatase. The three dimensional structure of HPSP reveals the structural and functional role of the divalent cation in the active site of phosphatases. In particular, the complex structures reveal that the open-closed environmental change of the active site, generated by local rearrangement of the alpha-helical bundle domain, is important for the substrate recognition and hydrolysis.

NCBI Accession: NP_004568

Pathways: Warburg Effekt