GMNN
Reaktivität: Human
ELISA, IF
Wirt: Kaninchen
Monoclonal
8H8
unconjugated
Recombinant Antibody
Applikationshinweise
Recommended dilution 1:500
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C,-80 °C
Informationen zur Lagerung
Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
Target
Geminin (GMNN)
(Geminin, DNA Replication Inhibitor (GMNN))
Andere Bezeichnung
Geminin
Hintergrund
Geminin is a 25 kDa protein, which inhibits DNA replication and is degraded during the mitotic phase of the cell cycle. Geminin controls replication by binding to the licensing factor Cdt1, and is involved in neural differentiation. In addition, geminin directly interacts with Six3 and Hox homeodomain proteins during embryogenesis and inhibits their functions.