Geminin Antikörper (AA 1-209)

Produktnummer ABIN165400

Produktdetails anti-Geminin Antikörper

Target: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Bindungsspezifität: AA 1-209

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Geminin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Immunogen: Recombinant human Geminin (1-209 aa) purified from E. coli

Klon: 2H7

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Recommended dilution 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu Geminin

Target: Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))

Andere Bezeichnung: Geminin (GMNN Produkte)

Hintergrund: Geminin is a 25 kDa protein, which inhibits DNA replication and is degraded during the mitotic phase of the cell cycle. Geminin controls replication by binding to the licensing factor Cdt1, and is involved in neural differentiation. In addition, geminin directly interacts with Six3 and Hox homeodomain proteins during embryogenesis and inhibits their functions.

NCBI Accession: NP_056979

Pathways: EGFR Signaling Pathway, DNA Replication