PARL Antikörper (C-Term)
Kurzübersicht für PARL Antikörper (C-Term) (ABIN1607894)
Target
Alle PARL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Hersteller Produkt- Nr.
- 600-401-j27
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Hersteller
- Rockland
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Verwendungszweck
- PARL Antibody
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Kreuzreaktivität (Details)
- This antibody is specific towards PARL.
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Produktmerkmale
- Synonyms: rabbit anti-PARL antibody, p-beta, Pbeta, presenilin associated rhomboid-like protein mitochondrial, PRO2207, Mitochondrial intramembrane cleaving protease PARL, PSARL
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Aufreinigung
- Anti-PARL was affinity purified from monospecific antiserum by immunoaffinity chromatography.
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Sterilität
- Sterile filtered
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Immunogen
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Immunogen: PARL affinity purified antibody was prepared from whole rabbit serum produced by repeated immunization from a synthetic peptide corresponding to the C terminus region of human PARL.
Immunogen Type: Conjugated Peptide
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Applikationshinweise
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Immunohistochemistry Dilution: 1:100-1:500
Application Note: Anti-PARL antibody is useful for ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~42.2 kDa corresponding to the appropriate cell lysate or extract.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1:20,000 - 1:60,000
IF Microscopy Dilution: 1:100-1:500
Other: User Optimized
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.86 mg/mL
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Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
Preservative: None -
Konservierungsmittel
- Without preservative
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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Haltbarkeit
- 6 months
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- PARL (Presenilin Associated, Rhomboid-Like (PARL))
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Andere Bezeichnung
- PARL
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Hintergrund
- Background: PARL (presenilin associated, rhomboid-like) encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. Anti-PARL antibodies are ideal for researchers interested in Apoptosis, Alzheimer's Research, Neuroscience, and Mitochondrial Fusion Proteins research.
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Gen-ID
- 55486
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NCBI Accession
- NP_061092
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UniProt
- Q9H300
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Pathways
- Autophagie
Target
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