PARL Antikörper (C-Term)

Produktnummer ABIN1607894

Hersteller Produkt- Nr.: 600-401-j27

Der Kaninchen Polyklonal anti-PARL Antikörper wird verwendet zum Nachweis von PARL in Proben von Human, Maus, Ratte, Huhn und Primate. Er wurde validiert für ELISA, WB, IHC und FM.

Kurzübersicht für PARL Antikörper (C-Term) (ABIN1607894)

Target: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Reaktivität: Human, Maus, Ratte, Huhn, Primate

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARL Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Produktdetails anti-PARL Antikörper

Bindungsspezifität: C-Term

Hersteller Produkt- Nr.: 600-401-j27

Hersteller: Rockland

Verwendungszweck: PARL Antibody

Kreuzreaktivität (Details): This antibody is specific towards PARL.

Produktmerkmale: Synonyms: rabbit anti-PARL antibody, p-beta, Pbeta, presenilin associated rhomboid-like protein mitochondrial, PRO2207, Mitochondrial intramembrane cleaving protease PARL, PSARL

Aufreinigung: Anti-PARL was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Sterilität: Sterile filtered

Immunogen:

Immunogen: PARL affinity purified antibody was prepared from whole rabbit serum produced by repeated immunization from a synthetic peptide corresponding to the C terminus region of human PARL.

Immunogen Type: Conjugated Peptide

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 1:100-1:500

Application Note: Anti-PARL antibody is useful for ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~42.2 kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 1 μg/mL

ELISA Dilution: 1:20,000 - 1:60,000

IF Microscopy Dilution: 1:100-1:500

Other: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.86 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: None

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 6 months

Details zu PARL

Target: PARL (Presenilin Associated, Rhomboid-Like (PARL))

Andere Bezeichnung: PARL

Hintergrund: Background: PARL (presenilin associated, rhomboid-like) encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. Anti-PARL antibodies are ideal for researchers interested in Apoptosis, Alzheimer's Research, Neuroscience, and Mitochondrial Fusion Proteins research.

Gen-ID: 55486

NCBI Accession: NP_061092

UniProt: Q9H300

Pathways: Autophagie