Huntingtin Antikörper (C-Term)

Produktnummer ABIN1607891

Hersteller Produkt- Nr.: 600-401-j24

Der Kaninchen Polyklonal Anti-Huntingtin-Antikörper wurde für IHC, WB, ELISA und FM validiert. Er ist geeignet, Huntingtin in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für Huntingtin Antikörper (C-Term) (ABIN1607891)

Target: Huntingtin (HTT)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Huntingtin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)

Produktdetails anti-Huntingtin Antikörper

Bindungsspezifität: C-Term

Hersteller Produkt- Nr.: 600-401-j24

Hersteller: Rockland

Verwendungszweck: Huntington Antibody

Kreuzreaktivität (Details): This antibody is specific towards HTT.

Produktmerkmale: Synonyms: rabbit anti-Huntington antibody, rabbit anti-Huntingtin antibody, HD protein, HTT, Huntington Disease Protein, Huntington disease, IT15, LOMARS

Aufreinigung: Anti-Huntingtin was affinity purified from monospecific antiserum by immunoaffinity chromatography.

Sterilität: Sterile filtered

Immunogen:

Immunogen: Huntington affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to the C-terminus of human Huntington disease protein.

Immunogen Type: Conjugated Peptide

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 1:100-1:500

Application Note: Anti-Huntingtin antibody is useful for ELISA and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~350 kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 0.1 μg/mL

ELISA Dilution: 1:20,000 - 1:60,000

IF Microscopy Dilution: 1:100-1:500

Other: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 30 % Glycerol

Preservative: None

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Haltbarkeit: 6 months

Details zu Huntingtin

Target: Huntingtin (HTT)

Andere Bezeichnung: HTT

Hintergrund: Background: Huntington's disease (HD) is an autosomal dominant neurological disorder caused by a polyglutamine (polyQ) repeat expansion in the huntingtin (HTT) protein. The disease is characterized by neurodegeneration and formation of neuronal intracellular inclusions primarily in the striatum and cortex, leading to personality changes, motor impairment, and dementia. The Huntington's disease protein is ~350kD in size and is localized in the brain. Anti-Huntingtin antibodies are ideal for researchers interested in Apoptosis, Autophagy, Cytoskeleton, Neurodegeneration, Neuroscience, and Neuronal Cell Markers research.

Gen-ID: 3064

NCBI Accession: NP_002102

UniProt: P42858

Pathways: PI3K-Akt Signalweg, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport