TIE1 Antikörper

Produktnummer ABIN1589940

Der Kaninchen Polyklonal anti-TIE1 Antikörper (ABIN1589940) detektiert spezifisch TIE1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für TIE1 Antikörper (ABIN1589940)

Target: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TIE1 Antikörper

Verwendungszweck: Rabbit Anti-Mouse TIE-1 Polyclonal Antibody

Spezifität: Recombinant mouse sTIE-1

Produktmerkmale: Chromosomal location: 4 D2.1, 4 50.0 cM

Aufreinigung: Protein A purified

Immunogen: Recombinant mouse sTIE-1 ( (ABIN1589959)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: use at 2-5 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Handhabung: Centrifuge vial prior to opening.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Haltbarkeit: 24 months

Details zu TIE1

Target: TIE1 (tyrosine Kinase with Immunoglobulin-Like and EGF-Like Domains 1 (TIE1))

Andere Bezeichnung: TIE-1

Hintergrund:

Synonyms: Tie1, TIE, tie-1, D430008P04Rik

Description: TIE-1 (tyrosine kinase with Ig and EGF homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin-like domains flanking three epidermal growth factor (EGF)-like domains and followed by three fibronectin type III-like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. These receptors are expressed primarily on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis.

Gen-ID: 21846

NCBI Accession: NM_011587, NP_035717

UniProt: Q06806

Pathways: RTK Signalweg