LIF Antikörper

Produktnummer ABIN1589881

Produktdetails anti-LIF Antikörper

Target: LIF (Leukemia Inhibitory Factor (LIF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Recombinant human LIF

Produktmerkmale: Chromosomal location: 22q12.2
Produced from sera of rabbits immunized with highly pure recombinant human Leukemina Inhibitory Factor (LIF) [Ser23 - Phe202, produced in E. coli].

Aufreinigung: Anti-human LIF was purified by affinity chromatography with immobilized Protein A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: use 2-5 µg/mL

Kommentare:

Rabbit IG Polyclonal Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Handhabung: Centrifuge vial prior to opening.

Lagerung: -20 °C

Informationen zur Lagerung: The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C

Haltbarkeit: 6 months

Details zu LIF

Target: LIF (Leukemia Inhibitory Factor (LIF))

Andere Bezeichnung: LIF (LIF Produkte)

Synonyme: CDF antikoerper, DIA antikoerper, HILDA antikoerper, MLPLI antikoerper, LIF, interleukin 6 family cytokine antikoerper, leukemia inhibitory factor antikoerper, LIF antikoerper, Lif antikoerper

Hintergrund: Leukemia Inhibitory Factor also called LIF is a lymphoid factor that promotes long-term maintenance of embryonic stem cells by suppressing spontaneous differentiation. Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Human and mouse LIF exhibit a 78% identity in its amino acid sequence. Human LIF is as active on human cells as is it is on mouse cells, though mouse LIF is about 1000 fold less active on human cells, than human LIF.
Synonyms: LIF, CDF, DIA, HILDA, MLPLI

NCBI Accession: NP_002300, NM_002309

UniProt: P15018

Pathways: JAK-STAT Signalweg, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Stem Cell Maintenance, Growth Factor Binding