Tissue factor Antikörper (FITC)

Produktnummer ABIN155194

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Tissue factor in FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für Tissue factor Antikörper (FITC) (ABIN155194)

Target: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Tissue factor Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: CLB-TF-5

Produktdetails anti-Tissue factor Antikörper (FITC)

Spezifität: This antibody recognises CD142. The CLB/TF-5 antibody has been used successfully in an ELISA assay as a coating antibody in association with clone CLB/TF-1 (Cat.-No AM01050PU-N), which recognises a different epitope of CD142.

Aufreinigung: Affinity Chromatography on Protein A from tissue culture supernantant.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: Tris buffered saline, pH 8.0 containing, 0.09 % Sodium Azide, 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-Tissue factor Antikörper (FITC) (ABIN155194)

Rancourt, Veress, Guo, Jones, Hendry-Hofer, White: "Airway tissue factor-dependent coagulation activity in response to sulfur mustard analog 2-chloroethyl ethyl sulfide." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 302, Issue 1, pp. L82-92, (2012) (PubMed).

Details zu Tissue factor

Target: Tissue factor (F3) (Coagulation Factor III (thromboplastin, Tissue Factor) (F3))

Andere Bezeichnung: CD142 / Tissue Factor

Hintergrund: CD142 is a 45kD cell surface glycoprotein which is otherwise known as Tissue Factor (TF). CD142 expression can be induced on monocytes, macrophages and endothelial cells by various stimuli including interleukin 1, tumour necrosis factor and endotoxin. CD142 initiates the blood clotting cascade by binding coagulation factor VIIa, which activates factor IX or factor X by specific limited proteolysis. CD142 also plays an important role in inflammation, angiogenesis, and the pathophysiology of atherosclerosis and cancer.Synonyms: Coagulation factor III, F3, TF, Thromboplastin

Gen-ID: 2152

NCBI Accession: NP_001984

UniProt: P13726

Pathways: Positive Regulation of Endopeptidase Activity, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling