TEK Antikörper (Extracellular Domain) (Biotin)

Produktnummer ABIN155164

Dieser Maus Monoklonal Antikörper detektiert spezifisch TEK in WB, FACS und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TEK Antikörper (Extracellular Domain) (Biotin) (ABIN155164)

Target: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TEK Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Klon: Cl-9

Produktdetails anti-TEK Antikörper (Biotin)

Bindungsspezifität: Extracellular Domain

Spezifität: The unconjugated antibody will detect native TIE-2/tek.

Aufreinigung: Protein G chromatography

Immunogen: Recombinant human soluble extracellular TIE-2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot. FACS analysis and cell sorting: 2-5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Reconstitute to a concentration of 50 μg/mL with sterile PBS solution containing 0.1 % BSA

Buffer: 0.1 M Tris-Cl, 0.1 M NaCl, 0.02 % NaN3, pH 7.4 containing 50x BSA as stabilizer

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: This product is photosensitive and should be protected from light

Lagerung: 4 °C

Informationen zur Lagerung: Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Details zu TEK

Target: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Andere Bezeichnung: CD202b / TEK

Hintergrund: TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations, the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK

Gen-ID: 7010

NCBI Accession: NP_000450

UniProt: Q02763

Pathways: RTK Signalweg, Growth Factor Binding