TEK Antikörper (Extracellular Domain) (Biotin)

Produktnummer ABIN155163

Der Biotin-konjugierte Maus Monoklonal anti-TEK Antikörper (Klon Cl-2) (ABIN155163) detektiert spezifisch TEK in WB, FACS und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TEK Antikörper (Extracellular Domain) (Biotin) (ABIN155163)

Target: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TEK Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Klon: Cl-2

Produktdetails anti-TEK Antikörper (Biotin)

Bindungsspezifität: Extracellular Domain

Spezifität: The unconjugated Monoclonal antibody will detect native Human TIE-2/tek in ELISA experiments and on the surface of different Human cell types.

Aufreinigung: Protein G Chromatography

Immunogen: Recombinant Human soluble extracellular domain of TIE-2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: FACS analysis and cell sorting: 2-5 μg/mL. ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore to a concentration of 50 μg/mL with sterile PBS solution containing 0.1 % BSA.

Buffer: 0.1 M Tris-Cl, 0.1 M NaCl, pH 7.4, 0.02 % Sodium Azide, 50x BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: This product is photosensitive and should be protected from light

Lagerung: 4 °C

Informationen zur Lagerung: Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Details zu TEK

Target: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Andere Bezeichnung: CD202b / TEK

Hintergrund: TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations, the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK

Gen-ID: 7010

NCBI Accession: NP_000450

UniProt: Q02763

Pathways: RTK Signalweg, Growth Factor Binding