HMOX1 Antikörper (N-Term)

Produktnummer ABIN155124

Produktdetails anti-HMOX1 Antikörper

Target: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMOX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: The antibody recognizes ~32 kDa Heme-Oxygenase-1.

Aufreinigung: Affinity Chromatography

Immunogen: Synthetic peptide surrounding amino acid near the N-terminus of Human HO-1

Anwendungsinformationen

Applikationshinweise: Western Blot: 0.5-2 μg/mL. Immunoprecipitation: 10-20 μg/mL. Immunohistochemistry: 10-20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS, 0.5 % BSA, 30 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Details zu HMOX1

Target: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Andere Bezeichnung: Heme Oxygenase 1 / HMOX1 (HMOX1 Produkte)

Synonyme: HMOX1 antikoerper, ARABIDOPSIS THALIANA HEME OXYGENASE 1 antikoerper, ATHO1 antikoerper, F18A8.4 antikoerper, F18A8_4 antikoerper, GENOMES UNCOUPLED 2 antikoerper, GUN2 antikoerper, HEME OXYGENASE antikoerper, HEME OXYGENASE 1 antikoerper, HEME OXYGENASE 6 antikoerper, HO1 antikoerper, HY1 antikoerper, HY6 antikoerper, PLASTID HEME OXYGENASE antikoerper, REVERSAL OF THE DET PHENOTYPE 4 antikoerper, HO-1 antikoerper, wu:fc27c04 antikoerper, zgc:65984 antikoerper, D8Wsu38e antikoerper, Hemox antikoerper, Hmox antikoerper, Hsp32 antikoerper, HEOXG antikoerper, Heox antikoerper, Ho-1 antikoerper, Ho1 antikoerper, hsp32 antikoerper, MGC132176 antikoerper, Hmox1 antikoerper, HMOX1D antikoerper, HSP32 antikoerper, bK286B10 antikoerper, heme oxygenase 1 antikoerper, Plant heme oxygenase (decyclizing) family protein antikoerper, Heme oxygenase antikoerper, heme oxygenase antikoerper, heme oxygenase 1, chloroplastic antikoerper, heme oxygenase 1a antikoerper, heme oxygenase 1 L homeolog antikoerper, HMOX1 antikoerper, TED4 antikoerper, ho1 antikoerper, P9301_RS17555 antikoerper, A9601_RS17590 antikoerper, MAE_RS06565 antikoerper, HO1 antikoerper, hmox1a antikoerper, CPE0214 antikoerper, Cyan7425_2962 antikoerper, Hmox1 antikoerper, hmox1.L antikoerper, AM1_C0205 antikoerper, CC1G_11686 antikoerper, CpipJ_CPIJ007246 antikoerper

Hintergrund: Heme oxygenase-1 (HO-1) or HSP32 is the inducible isoform of heme oxygenase which catalyzes the NADPH, O2 and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, iron and biliverdin that is immediately reduced to bilirubin. To date, three heme oxygenase isoforms HO-1, HO-2 and HO-3 have been identified. HO-1, also known as Hsp32, a major heat shock/stress response protein, is ubiquitous and its mRNA as well as its activity can be increased several-fold by heme, other metalloporphyrins, transition metals and stimuli that induce cellular stress. The 5'-untranslated region (UTR) of HO-1 has several consensus regulatory elements that include sites for activator protein 1 (AP-1), metal responsive element (MRE), oncogene c-myc/max heterodimer binding site (Myc/Max), antioxidant response element (ARE) and GC box binding (Sp1). HO-1 expression has been shown to increase in benign postatic hyperplasia (BPH) and malignant prostate tissue suggesting a role for this stress protein in the pathogenesis of BPH and prostate cancer.Synonyms: HO, HO-1, HO1

Gen-ID: 3162

NCBI Accession: NP_002124

UniProt: P09601

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interaktom