PCDHGC4 Antikörper (N-Term)

Produktnummer ABIN1539248

Der Kaninchen Polyklonal Anti-PCDHGC4-Antikörper wurde für WB validiert. Er ist geeignet, PCDHGC4 in Proben von Human zu detektieren.

Kurzübersicht für PCDHGC4 Antikörper (N-Term) (ABIN1539248)

Target: PCDHGC4 (Protocadherin gamma Subfamily C, 4 (PCDHGC4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHGC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB39610

Produktdetails anti-PCDHGC4 Antikörper

Bindungsspezifität: AA 265-291, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHGC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-291 amino acids from the N-terminal region of human PCDHGC4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: PCDHGC4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu PCDHGC4

Target: PCDHGC4 (Protocadherin gamma Subfamily C, 4 (PCDHGC4))

Andere Bezeichnung: PCDHGC4

Hintergrund: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Molekulargewicht: 101214

Gen-ID: 56098

NCBI Accession: NP_061751, NP_115782

UniProt: Q9Y5F7