RNF144B Antikörper (AA 90-118)

Produktnummer ABIN1538681

Der Kaninchen Polyklonal Anti-RNF144B-Antikörper wurde für WB validiert. Er ist geeignet, RNF144B in Proben von Human zu detektieren.

Kurzübersicht für RNF144B Antikörper (AA 90-118) (ABIN1538681)

Target: RNF144B (Ring Finger Protein 144B (RNF144B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF144B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB37984

Produktdetails anti-RNF144B Antikörper

Bindungsspezifität: AA 90-118

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RNF144B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-118 amino acids from the Central region of human RNF144B.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: RNF144B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu RNF144B

Target: RNF144B (Ring Finger Protein 144B (RNF144B))

Andere Bezeichnung: RNF144B

Hintergrund: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death, But, it is not an anti-apoptotic protein per se.

Molekulargewicht: 33697

Gen-ID: 255488

NCBI Accession: NP_877434

UniProt: Q7Z419