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RNF144B Antikörper (Internal Region)

RNF144B Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258475
  • Target Alle RNF144B Antikörper anzeigen
    RNF144B (Ring Finger Protein 144B (RNF144B))
    Bindungsspezifität
    • 15
    • 7
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 43
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 35
    • 9
    Kaninchen
    Klonalität
    • 36
    • 8
    Polyklonal
    Konjugat
    • 14
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RNF144B Antikörper ist unkonjugiert
    Applikation
    • 29
    • 25
    • 13
    • 13
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    RNF144B Antibody detects endogenous levels of total RNF144B.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human RNF144B, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product RNF144B Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    RNF144B (Ring Finger Protein 144B (RNF144B))
    Andere Bezeichnung
    RNF144B (RNF144B Produkte)
    Synonyme
    IBRDC2 antikoerper, PIR2 antikoerper, bA528A10.3 antikoerper, p53RFP antikoerper, BC025007 antikoerper, E130105P19Rik antikoerper, Ibrdc2 antikoerper, Pir2 antikoerper, ring finger protein 144B antikoerper, RNF144B antikoerper, Rnf144b antikoerper
    Hintergrund

    Description: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a p53/TP53-dependent but caspase-independent mechanism. However, its overexpression also produces a decrease of the ubiquitin-dependent stability of BAX, a pro-apoptotic protein, ultimately leading to protection of cell death, But, it is not an anti-apoptotic protein per se.

    Gene: RNF144B

    Molekulargewicht
    33 kDa
    Gen-ID
    255488
    UniProt
    Q7Z419
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