SOCS7 Antikörper (C-Term)

Produktnummer ABIN1537362

Der Kaninchen Polyklonal anti-SOCS7 Antikörper (Klon RB37084) (ABIN1537362) detektiert spezifisch SOCS7 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SOCS7 Antikörper (C-Term) (ABIN1537362)

Target: SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOCS7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB37084

Produktdetails anti-SOCS7 Antikörper

Bindungsspezifität: AA 458-486, C-Term

Homologie: M

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SOCS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-486 amino acids from the C-terminal region of human SOCS7.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: SOCS7 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu SOCS7

Target: SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))

Andere Bezeichnung: SOCS7

Hintergrund: Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).

Molekulargewicht: 62969

Gen-ID: 30837

NCBI Accession: NP_055413

UniProt: O14512