RNF14 Antikörper (C-Term)

Produktnummer ABIN1537160

Der Kaninchen Polyklonal Anti-RNF14-Antikörper wurde für WB validiert. Er ist geeignet, RNF14 in Proben von Human zu detektieren.

Kurzübersicht für RNF14 Antikörper (C-Term) (ABIN1537160)

Target: RNF14 (Ring Finger Protein 14 (RNF14))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB30406

Produktdetails anti-RNF14 Antikörper

Bindungsspezifität: AA 336-364, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RNF14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-364 amino acids from the C-terminal region of human RNF14.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: RNF14 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu RNF14

Target: RNF14 (Ring Finger Protein 14 (RNF14))

Andere Bezeichnung: RNF14

Hintergrund: The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.

Molekulargewicht: 53837

Gen-ID: 9604

NCBI Accession: NP_001188294, NP_004281, NP_899645, NP_899646, NP_899647, NP_899648

UniProt: Q9UBS8

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling