NTAN1 Antikörper (C-Term)

Produktnummer ABIN1536839

Der Kaninchen Polyklonal Anti-NTAN1-Antikörper wurde für WB validiert. Er ist geeignet, NTAN1 in Proben von Human zu detektieren.

Kurzübersicht für NTAN1 Antikörper (C-Term) (ABIN1536839)

Target: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NTAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB37947

Produktdetails anti-NTAN1 Antikörper

Bindungsspezifität: AA 203-230, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NTAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-230 amino acids from the C-terminal region of human NTAN1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: NTAN1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu NTAN1

Target: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Andere Bezeichnung: NTAN1

Hintergrund: Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N-terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position (By similarity).

Gen-ID: 123803

NCBI Accession: NP_001257695, NP_001257696, NP_775745

UniProt: Q96AB6