CASC5 Antikörper (C-Term)

Produktnummer ABIN1536748

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CASC5 in WB. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für CASC5 Antikörper (C-Term) (ABIN1536748)

Target: CASC5 (Cancer Susceptibility Candidate 5 (CASC5))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CASC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB40173

Produktdetails anti-CASC5 Antikörper

Bindungsspezifität: AA 1557-1583, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Casc5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1557-1583 amino acids from the C-terminal region of mouse Casc5.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Mouse Casc5 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu CASC5

Target: CASC5 (Cancer Susceptibility Candidate 5 (CASC5))

Andere Bezeichnung: Casc5

Hintergrund: Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Directly links spindle checkpoint proteins BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore (By similarity).

Gen-ID: 76464

UniProt: Q66JQ7

Pathways: Maintenance of Protein Location, Autophagie