HMGB1 Antikörper (C-Term)

Produktnummer ABIN1536601

Dieses Maus Monoklonal-Antikörper erkennt spezifisch HMGB1 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für HMGB1 Antikörper (C-Term) (ABIN1536601)

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HMGB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 393CT23-1-4

Produktdetails anti-HMGB1 Antikörper

Bindungsspezifität: AA 152-180, C-Term

Homologie: B, Ha, Hs, Pr, Pig, Rat

Aufreinigung: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This HMGB1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the C-terminal region of human HMGB1.

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1600. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: HMGB1 Antibody (C-term) (Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu HMGB1

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Andere Bezeichnung: HMGB1

Hintergrund: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).

Molekulargewicht: 24894

Gen-ID: 3146

NCBI Accession: NP_002119

UniProt: P09429

Pathways: p53 Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome