MMP17 Antikörper (Cleaved-Gln129)

Produktnummer ABIN1536144

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MMP17 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für MMP17 Antikörper (Cleaved-Gln129) (ABIN1536144)

Target: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MMP17 Antikörper

Bindungsspezifität: AA 110-159, Cleaved-Gln129

Verwendungszweck: Cleaved-MMP-17 (Q129) Antibody

Spezifität: Cleaved-MMP-17 (Q129) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-17 protein resulting from cleavage adjacent to Q129.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MMP17. AA range:110-159

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MMP17

Target: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Andere Bezeichnung: MMP17

Hintergrund:

Synonyms: MMP17, MT4MMP, Matrix metalloproteinase-17, MMP-17, Membrane-type matrix metalloproteinase 4, MT-MMP 4, MTMMP4, Membrane-type-4 matrix metalloproteinase, MT4-MMP, MT4MMP

Background: This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor. Elevated expression of the encoded protein has been observed in osteoarthritis and multiple human cancers. [provided by RefSeq, Jan 2016],

Gene Name: MMP17

Protein Name: Matrix metalloproteinase-17

Molekulargewicht: 53 kDa

Gen-ID: 4326

OMIM: 602285

UniProt: Q9ULZ9