CD51 Antikörper (Cleaved-Lys889)

Produktnummer ABIN1536136

Der Kaninchen Polyklonal anti-CD51 Antikörper wird verwendet zum Nachweis von CD51 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für CD51 Antikörper (Cleaved-Lys889) (ABIN1536136)

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD51 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CD51 Antikörper

Bindungsspezifität: AA 840-889, Cleaved-Lys889

Verwendungszweck: Cleaved-Integrin αV HC (K889) Antibody

Spezifität: Cleaved-Integrin αV HC (K889) Polyclonal Antibody detects endogenous levels of fragment of activated Integrin αV HC protein resulting from cleavage adjacent to K889.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ITGAV. AA range:840-889

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu CD51

Target: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Andere Bezeichnung: ITGAV

Hintergrund:

Synonyms: ITGAV, MSK8, VNRA, Integrin alpha-V, Vitronectin receptor subunit alpha, CD antigen CD51

Background: integrin subunit alpha V(ITGAV) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015],

Gene Name: ITGAV

Protein Name: Integrin alpha-V

Molekulargewicht: 95 kDa

Gen-ID: 3685

OMIM: 193210

UniProt: P06756

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex