Cathepsin D Antikörper (Cleaved-Gly65)

Produktnummer ABIN1536109

Der Kaninchen Polyklonal anti-Cathepsin D Antikörper wird verwendet zum Nachweis von Cathepsin D in Proben von Human und Affe. Er wurde validiert für WB und ELISA.

Kurzübersicht für Cathepsin D Antikörper (Cleaved-Gly65) (ABIN1536109)

Target: Cathepsin D (CTSD)

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Cathepsin D Antikörper

Bindungsspezifität: AA 46-95, Cleaved-Gly65

Verwendungszweck: Cleaved-Cathepsin D LC (G65) Antibody

Spezifität: Cleaved-Cathepsin D LC (G65) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin D LC protein resulting from cleavage adjacent to G65.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CATD. AA range:46-95

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Cathepsin D

Target: Cathepsin D (CTSD)

Andere Bezeichnung: CATD

Hintergrund:

Synonyms: CTSD; CPSD; Cathepsin D

Background: This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015],

Gene Name: CTSD

Protein Name: Cathepsin D

Molekulargewicht: 17 kDa

Gen-ID: 1509

OMIM: 116840

UniProt: P07339

Pathways: Peptide Hormone Metabolism