SLC38A2 Antikörper (AA 151-200)

Produktnummer ABIN1535505

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SLC38A2 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SLC38A2 Antikörper (AA 151-200) (ABIN1535505)

Target: SLC38A2 (Solute Carrier Family 38, Member 2 (SLC38A2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC38A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SLC38A2 Antikörper

Bindungsspezifität: AA 151-200

Verwendungszweck: SNAT2 Antibody

Spezifität: SNAT2 Polyclonal Antibody detects endogenous levels of SNAT2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SLC38A2. AA range:151-200

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu SLC38A2

Target: SLC38A2 (Solute Carrier Family 38, Member 2 (SLC38A2))

Andere Bezeichnung: SLC38A2

Hintergrund:

Synonyms: SLC38A2, ATA2, KIAA1382, SAT2, SNAT2, Sodium-coupled neutral amino acid transporter 2, Amino acid transporter A2, Protein 40-9-1, Solute carrier family 38 member 2, System A amino acid transporter 2, System A transporter 1, System N amino a

Background: enzyme regulation:Inhibited by N-methyl-D-glucamine and probably choline.,function:Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH -sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta.,induction:Up-regulated upon hypertonic conditions and amino acid deprivation.,miscellaneous:Depletion of SCL38A2 by siRNA prevents the recovery of cells from hypertonic stress.,PTM:Polyubiquitination by NEDD4L regulates the degradation and the activity of SLC38A2.,similarity:Belongs to the amino acid/polyamine transporter 2 family.,subcellular location:Insulin promotes recruitment to the plasma membrane from a pool localized in the trans-Golgi network or endosomes (By similarity). Enriched in the somatodendritic compartment of neurons, it is also detected at the axonal shaft but excluded from the nerve terminal.,tissue specificity:Ubiquitously expressed. Widely expressed in the central nervous system with higher concentrations in caudal regions. Expressed by glutamatergic and GABAergic neurons together with astrocytes and other non-neuronal cells in the cerebral cortex (at protein level).,

Gene Name: SLC38A2

Protein Name: Sodium-coupled neutral amino acid transporter 2

Molekulargewicht: 56 kDa

Gen-ID: 54407

OMIM: 605180

UniProt: Q96QD8

Pathways: Dicarboxylic Acid Transport