SLC38A2 Antikörper (N-Term)

Produktnummer ABIN2777727

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-SLC38A2 Antikörper wird verwendet zum Nachweis von SLC38A2 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für SLC38A2 Antikörper (N-Term) (ABIN2777727)

Target: SLC38A2 (Solute Carrier Family 38, Member 2 (SLC38A2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC38A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SLC38A2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SLC38A2 Antibody - N-terminal region

Sequenz: AALKSHYADV DPENQNFLLE SNLGKKKYET EFHPGTTSFG MSVFNLSNAI

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC38A2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC38A2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8112306

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SLC38A2 Antikörper (ABIN2777727)

Hernandez-García, Manjarín, Suryawan, Nguyen, Davis, Orellana: "Amino acids, independent of insulin, attenuate skeletal muscle autophagy in neonatal pigs during endotoxemia." in: Pediatric research, Vol. 80, Issue 3, pp. 448-51, (2016) (PubMed).

Suryawan, Nguyen, Almonaci, Davis: "Abundance of amino acid transporters involved in mTORC1 activation in skeletal muscle of neonatal pigs is developmentally regulated." in: Amino acids, Vol. 45, Issue 3, pp. 523-30, (2013) (PubMed).

Details zu SLC38A2

Target: SLC38A2 (Solute Carrier Family 38, Member 2 (SLC38A2))

Andere Bezeichnung: SLC38A2

Hintergrund:

Background Information: Under hypertonic conditions the induction of SLC38A2/SNAT2 leads to the stimulation of transport system A and to the increase in the cell content of amino acids. Its amino acid response element, along with a nearby conserved CAAT box, has enhancer activity in that it functions in an orientation and position independent manner, and it confers regulated transcription to a heterologous promoter.

Gene Name: Solute carrier family 38, member 2

Alternative Symbols: ATA2, SAT2, SNAT2, PRO1068

Protein Name: Sodium-coupled neutral amino acid transporter 2

Molekulargewicht: 56 kDa

Gen-ID: 54407

NCBI Accession: NP_061849

UniProt: Q96QD8

Pathways: Dicarboxylic Acid Transport