ARHGEF7 Antikörper (AA 311-360)
Kurzübersicht für ARHGEF7 Antikörper (AA 311-360) (ABIN1535301)
Target
Alle ARHGEF7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 311-360
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Verwendungszweck
- PIXβ Antibody
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Spezifität
- PIXβ Polyclonal Antibody detects endogenous levels of PIXβ protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human ARHGEF7. AA range:311-360
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
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Andere Bezeichnung
- ARHGEF7
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Hintergrund
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Synonyms: ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB, Nbla10314, Rho guanine nucleotide exchange factor 7, Beta-Pix, COOL-1, PAK-interacting exchange factor beta, p85
Background: This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Mar 2016],
Gene Name: ARHGEF7
Protein Name: Rho guanine nucleotide exchange factor 7
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Molekulargewicht
- 90 kDa
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Gen-ID
- 8874
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OMIM
- 605477
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UniProt
- Q14155
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Pathways
- EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation
Target
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