nectin-3 Antikörper (AA 184-233)

Produktnummer ABIN1535178

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch nectin-3 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für nectin-3 Antikörper (AA 184-233) (ABIN1535178)

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser nectin-3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-nectin-3 Antikörper

Bindungsspezifität: AA 184-233

Verwendungszweck: Nectin 3 Antibody

Spezifität: Nectin 3 Polyclonal Antibody detects endogenous levels of Nectin 3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PVRL3. AA range:184-233

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu nectin-3

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Andere Bezeichnung: PVRL3

Hintergrund:

Synonyms: PVRL3, PRR3, Poliovirus receptor-related protein 3, CDw113, Nectin-3, CD antigen CD113

Background: This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011],

Gene Name: PVRL3

Protein Name: Poliovirus receptor-related protein 3

Molekulargewicht: 61 kDa

Gen-ID: 25945

OMIM: 607147

UniProt: Q9NQS3

Pathways: Cell-Cell Junction Organization