NOX3 Antikörper (AA 287-336)

Produktnummer ABIN1535076

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch NOX3 in ELISA, WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.Es wurde in 1 Publikation zitiert.

Kurzübersicht für NOX3 Antikörper (AA 287-336) (ABIN1535076)

Target: NOX3 (NADPH Oxidase 3 (NOX3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOX3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-NOX3 Antikörper

Bindungsspezifität: AA 287-336

Verwendungszweck: Nox3 Antibody

Spezifität: Nox3 Polyclonal Antibody detects endogenous levels of Nox3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human NOX3. AA range:287-336

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Referenzen für anti-NOX3 Antikörper (ABIN1535076)

Du, Yang, Hu, Sun, Zhang, Peng, Zhong, Huang, Kong: "A long-term high-fat diet increases oxidative stress, mitochondrial damage and apoptosis in the inner ear of D-galactose-induced aging rats." in: Hearing research, Vol. 287, Issue 1-2, pp. 15-24, (2012) (PubMed).

Details zu NOX3

Target: NOX3 (NADPH Oxidase 3 (NOX3))

Andere Bezeichnung: NOX3

Hintergrund:

Synonyms: NOX3, MOX2, NADPH oxidase 3, Mitogenic oxidase 2, MOX-2, gp91phox homolog 3, GP91-3

Background: This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation.The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.[provided by RefSeq, May 2009],

Gene Name: NOX3

Protein Name: NADPH oxidase 3

Molekulargewicht: 64 kDa

Gen-ID: 50508

OMIM: 607105

UniProt: Q9HBY0