GRAP Antikörper (AA 1-50)

Produktnummer ABIN1534946

Der Kaninchen Polyklonal anti-GRAP Antikörper (ABIN1534946) detektiert spezifisch GRAP in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GRAP Antikörper (AA 1-50) (ABIN1534946)

Target: GRAP (GRB2-Related Adaptor Protein (GRAP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-GRAP Antikörper

Bindungsspezifität: AA 1-50

Verwendungszweck: Grap Antibody

Spezifität: Grap Polyclonal Antibody detects endogenous levels of Grap protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GRAP. AA range:1-50

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu GRAP

Target: GRAP (GRB2-Related Adaptor Protein (GRAP))

Andere Bezeichnung: GRAP

Hintergrund:

Synonyms: GRAP, GRB2-related adapter protein

Background: This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. [provided by RefSeq, Jul 2012],

Gene Name: GRAP

Protein Name: GRB2-related adapter protein

Molekulargewicht: 25 kDa

Gen-ID: 10750

OMIM: 604330

UniProt: Q13588